RAF Typhoon FGR4s have joined forces with French warplanes in a joint strike against an hidden munitions depot in Syrian territory used by the IS group, as stated by the British defence ministry.
The location, pinpointed through surveillance, was assessed as containing munitions and bombs, the announcement noted, and was located in mountains just above Palmyra in the heart of Syria.
"Our fighter planes employed precision-guided Paveway IV munitions to target a series of access tunnels providing entry to the facility... early reports suggest the target was engaged successfully," the MoD said.
There was no evidence of any civilian impact in the strike late on Saturday and every plane involved returned to base without incident, the defence officials confirmed.
The Typhoon FGR4s were supported by a Voyager tanker plane.
The Islamic State group - referred to as Daesh - established jihadist rule over significant areas in both Syria and Iraq prior to its 2019 collapse.
"This strike demonstrates the UK's leading role, and determination to operate in unison with allied nations, to eradicate any revival of the terrorist group and their harmful and extremist ideologies in the area," UK Defence Secretary the Defence Secretary said.
UK warplanes have conducted patrols over Syria to "forestall any efforts to regroup" of the group after its routing at the climactic battle in Baghuz in 2019, the ministry said.
"I must thank every member of our armed forces who took part in this operation for their expertise and their bravery," he said. "They were among a great many British personnel on duty over the festive period. This action, to take out militants who threaten our security, highlights how British military are always on standby, throughout the year, ensuring Britain's security at home and powerful internationally."
In December, the US military executed what it termed a "large-scale strike" targeting Islamic State objectives in Syria, subsequent to an attack resulted in the deaths of two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations reports Daesh still has roughly 5-7 thousand fighters in Syria and Iraq.